Anti-T2R60 antibody (bs-12042R)

Anti-T2R60 antibody

DATASHEET

Host:Rabbit

Target Protein:T2R60

IR:Immunogen Range:41-140/318

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:338398

Swiss Prot:P59551

Source:KLH conjugated synthetic peptide derived from human T2R60:41-140/318 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:T2R60 is a 318 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. T2R60 acts as a receptor that may play a role in the perception of bitterness, and is also thought to be involved in sensing the chemical composition of gastrointestinal content. As a gustducin-linked receptor, the activity of T2R60 may stimulate G alpha (alpha gustducin), mediate PLC beta 2 activation and lead to the gating of TRPM5. While expressed in subsets of taste receptor cells of the tongue and palate epithelium, T2R60 is found exclusively in gustducin-positive cells. The gene that encodes T2R60 contains 957 bases and maps to human chromosome 7q35. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Bee
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Stomach (Mouse) Lysate at 40 ug
Primary: Anti- T2R60 (bs-12042R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 36 kD
Observed band size: 36 kD