Anti-SH3PX1 antibody
| 英文名称 | SH3PX1 |
| 中文名称 | 分选连接蛋白9抗体 |
| 别 名 | MST 155; MST155; MSTP 155; MSTP155; OTTHUMP00000040083; Protein SDP 1; Protein SDP1; SDP 1; SDP1; SH3 and PX domain containing protein 3A; SH3 and PX domain containing protein SH3PX1; SH3 and PX domain-containing protein 1; SH3 and PX domain-containing protein 3A; SH3PX1; SH3PXD3A; SNX 9; SNX9; SNX9_HUMAN; Sorting nexin 9; Sorting nexin-9; WASP interactor protein; Wiskott Aldrich syndrome protein (WASP) interactor protein; Wiskott Aldrich syndrome protein interactor protein; WISP. |
DATASHEET
Host:Rabbit
Target Protein:SH3PX1
IR:Immunogen Range:501-595/595
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:51429
Swiss Prot:Q9Y5X1
Source:KLH conjugated synthetic peptide derived from human SNX5:501-595/595
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNXs partially associate with cellular membranes, despite their hydrophilic nature. SNX9 resides in the cytosol where it influences the processing and trafficking of insulin receptors. The enzyme aldolase binds to and inactivates SNX9. Phosphorylation of SNX9 releases aldolase and frees SNX9 to recruit and activate Dynamin II, a neuronal phosphoprotein and a GTPase enzyme which mediates late stages of endocytosis in both neural and non-neural cells.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Pituitary (Mouse) Lysate at 40 ug
Lymph node (Mouse) Lysate at 40 ug
Kidney (Mouse) Lysate at 40 ug
Primary: Anti-SH3PX1 (bs-12407R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 67 kD
Observed band size: 67 kD
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