Anti-phospho-FANCD2 (Ser1404) antibody
| 英文名称 | phospho-FANCD2 (Ser1404) |
| 中文名称 | 磷酸化FANCD2抗体 |
| 别 名 | FANCD2 (phospho S1404); FANCD2 (phospho Ser1404); p-FANCD2 (phospho S1404); FA 4; FA D2; FA4; FAC D2; FACD 2; FACD; FACD2; FAD; FAD2; FANC D2; FANCD 2; FANCD; Protein FACD2; Type 4 Fanconi pancytopenia; FACD2_HUMAN; Fanconi anemia group D2 protein; Protein FACD2. |
DATASHEET
Host:Rabbit
Target Protein:phospho-FANCD2 (Ser1404)
IR:Immunogen Range:QN(p-S)QE
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2177
Swiss Prot:Q9BXW9
Source:KLH conjugated Synthesised phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser1404:QN(p-S)QE
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Flow-Cyt(1μg/Test)
Cross Reactive Species:Human
Pig
Cow
Horse
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Blank control(blue): Hela Cells( fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice).
Primary Antibody: Rabbit Anti-phospho-FANCD2(Ser1404)/AF488 Conjugated antibody (bs-13141R/AF488), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG/AF488 (orange) ,used under the same conditions.
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