Anti-GABPB2 antibody
| 英文名称 | GABPB2 |
| 中文名称 | GA结合蛋白转录因子β/GABP-β1/GABP-β2抗体 |
| 别 名 | MGC29891; BABPB2; E4TF1; E4TF1-47; E4TF1-53; E4TF1B; GA binding protein transcription factor beta subunit 1 transcript variant gamma 2; GA binding protein transcription factor, beta subunit 1; GA binding protein transcription factor, beta subunit 2; GA-binding protein subunit beta-1; GABP subunit beta-1; GABP subunit beta-2; GABP1_HUMAN; GABPB; GABPB-1; GABPB-2; GABPB1; GABPB2; NRF2B1; NRF2B2; Nuclear respiratory factor 2; Transcription factor E4TF1-47; Transcription factor E4TF1-53. |
DATASHEET
Host:Rabbit
Target Protein:GABPB2
IR:Immunogen Range:301-395/395
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2553
Swiss Prot:Q06547
Source:KLH conjugated synthetic peptide derived from human GABPB2/GABPB1:301-395/395
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, GABP beta. GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABP beta is expressed in both the cytoplasm and the nucleus, whereas GABP alpha is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo . The GABP alpha beta tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Cow
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Protein: A549(human) lysates at 30ug;
Primary: rabbit Anti-GABPB2 (bs-13262R) at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;
Predicted band size:42 kD
Observed band size:42 kD
好评度