Anti-GPR1 antibody (bs-13509R)

Anti-GPR1 antibody

DATASHEET

Host:Rabbit

Target Protein:GPR1

IR:Immunogen Range:171-270/355

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2825

Swiss Prot:P46091

Source:KLH conjugated synthetic peptide derived from human G protein coupled receptor 1:171-270/355 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. Gpr1 is required for yeast-to-hypha transition on various solid hypha-inducing media, and important for yeast cell morphology. It activates guanine nucleotide exchange on Gpa2 which stimulates cAMP synthesis by glucose. In Saccharomyces cerevisiae, Gpr1 is necessary for filamentous and invasive growth.

Size:100ul

Concentration:1mg/ml

Applications:

Cross Reactive Species:Human
Mouse
Rat
Dog
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample: A549 (human)Cell Lysate at 40 ug
Primary: Anti-GPR1(bs-13509R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kD
Observed band size: 41 kD