Anti-GPR27 antibody (bs-13528R)

Anti-GPR27 antibody    

DATASHEET

Host:Rabbit

Target Protein:GPR27

IR:Immunogen Range:251-350/375

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2850

Swiss Prot:Q9NS67

Source:KLH conjugated synthetic peptide derived from human SREB1:251-350/375 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. GPRs all have seven membrane-spanning domains and extracellular loops that can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. SREB1 (super conserved receptor expressed in brain 1), also known as GPR27 (G protein-coupled receptor 27), belongs to the SREB subfamily of GPRs that are expressed in the central nervous system. SREB1 may function as an amine-like GPR.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(3μg/Test)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Cow
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Blank control: RSC96 cells(blue).
Primary Antibody: Rabbit Anti- GPR27 antibody(bs-13528R), Dilution: 5μg in 100 μL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG (orange) ,used under the same conditions.
Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.