Anti-C9orf115 antibody (bs-15309R)

Anti-C9orf115 antibody 

DATASHEET

Host:Rabbit

Target Protein:C9orf115

IR:Immunogen Range:101-200/214

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:138428

Swiss Prot:Q86Y79

Source:KLH conjugated synthetic peptide derived from human C9orf115:101-200/214 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:PTRH1 is a 214 amino acid protein that belongs to the PTH family. The PTRH1 protein is believed to be involved in RNA splicing, silencing and metabolism. The PTRH1 gene is conserved in chimpanzee, dog, cow, mouse, rat, zebrafish, A.thaliana and rice, and maps to human chromosome 9q34.11. Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Size:100ul

Concentration:1mg/ml

Applications:IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (C9orf115) Polyclonal Antibody, Unconjugated (bs-15309R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.