Anti-GPR114 antibody (bs-15376R)

Anti-GPR114 antibody

DATASHEET

Host:Rabbit

Target Protein:GPR114

IR:Immunogen Range:1-100/523

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:221188

Swiss Prot:Q8IZF4

Source:KLH conjugated synthetic peptide derived from human GPR114:1-100/523 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR114 (G protein-coupled receptor 114), also known as G-protein coupled receptor PGR27, is a 528 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Containing one GPS domain and mapping to human chromosome 16, GPR114 functions as an orphan receptor. Chromosome 16 encodes over 900 genes, comprises nearly 3% of the human genome and is associated with both Rubinstein-Taybi syndrome and Crohn's disease.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Hela Cell(Human)Lysate at 30 ug
Primary: Anti- GPR114 (bs-15376R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57kD
Observed band size: 67kD