Anti-GPRC5C antibody (bs-15394R)

Anti-GPRC5C antibody

DATASHEET

Host:Rabbit

Target Protein:GPRC5C

IR:Immunogen Range:51-150/441

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:55890

Swiss Prot:Q9NQ84

Source:KLH conjugated synthetic peptide derived from human GPRC5C:51-150/441 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPRC5C (G protein-coupled receptor, family C, group 5, member C), also known as RAIG3, is a 441 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and belongs to the G protein-coupled receptor family. Expressed at high levels in stomach, liver, prostate, kidney and pancreas, GPRC5C is thought to function as a retinoic acid-inducible GPR that may play a role in signaling events throughout the cell. GPRC5C is subject to DNA damage-dependent phosphorylation, probably by ATM or ATR.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)

Cross Reactive Species:Human
Mouse
Rat
Pig
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Pancreas (Mouse) Lysate at 40 ug
Primary: Anti- GPRC5C (bs-15394R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD