Anti-HERPUD2 antibody (bs-15465R)

Anti-HERPUD2 antibody

DATASHEET

Host:Rabbit

Target Protein:HERPUD2

IR:Immunogen Range:21-120/406

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:64224

Swiss Prot:Q9BSE4

Source:KLH conjugated synthetic peptide derived from human HERPUD2:21-120/406 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The endoplasmic reticulum (ER) stress response is triggered by the accumulation of unfolded proteins within the ER and is characterized by three events: the inhibition of translation (to prevent further protein accumulation), the up-regulated expression of polypeptide-folding proteins (known as the unfolded protein response or UPR) and the degradation of misfolded proteins by the ER-associated protein degradation (ERAD) system. Members of the homocysteine-inducible and ER stress-inducible ubiquitin-like domain families are components of the ERAD system and, via their ubiquitin-like domain, are thought to be involved in the destruction of misfolded proteins. HERPUD2 (Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2) is a 406 amino acid single-pass membrane protein containing one N-terminal ubiquitin-like domain. HERPUD2 is thought to be involved in the unfolded protein response (UPR) pathway.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
HL-60 Cell (Human) Lysate at 40 ug
K562 Cell (Human) Lysate at 40 ug
Primary: Anti- HERPUD2 (bs-15465R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 50 kD