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Anti-phospho-14-3-3 Tau (Ser232) antibody (bs-13774R)

Anti-phospho-14-3-3 Tau (Ser232) antibody (bs-13774R)

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Anti-phospho-14-3-3 Tau (Ser232) antibody

英文名称phospho-14-3-3 Tau (Ser232)
中文名称磷酸化14-3-3 τ抗体
别    名14-3-3 Tau (phospho S232); p-14-3-3 Tau (phospho S232); 14 3 3 protein T cell; 14 3 3 protein tau; 14 3 3 protein theta; 14 3 3 tau; 14 3 3 theta; 14-3-3 protein T-cell; 14-3-3 protein tau; 14-3-3 protein theta; 1433T_HUMAN; 1C5; HS1; KCIP1; Protein HS1; Protein kinase C inhibitor protein 1; Protein tau; tyr3/trp5 monooJNCgenase activation protein, theta; Tyrosine 3 monooJNCgenase/tryptophan 5 monooJNCgenase activation protein, theta polypeptide; Ywhaq.  

DATASHEET

Host:Rabbit

Target Protein:phospho-14-3-3 Tau (Ser232)

IR:Immunogen Range:SD(p-S)AG

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:10971

Swiss Prot:P27348

Source:KLH conjugated synthesised phosphopeptide derived from human 14-3-3 Tau around the phosphorylation site of Ser232:SD(p-S)AG 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Blank control (blue line): HL60 (fixed with 70% ethanol (overninght at 4℃) and then permeabilized with 0.1% PBS-Tween for 20 min at room temperature).
Primary Antibody (green line): Rabbit Anti-phospho-14-3-3 Tau (Ser232) antibody (bs-13774R),Dilution: 1μg /10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG .
Secondary Antibody (white blue line): Goat anti-rabbit IgG-PE,Dilution: 1μg /test.

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