Anti-Phospho-LAT (Tyr171) antibody
| 英文名称 | Phospho-LAT (Tyr171) |
| 中文名称 | 磷酸化T细胞活化连接蛋白抗体 |
| 别 名 | LAT (Phospho Tyr171); LAT (Phospho Y171); p-LAT (Tyr171); p-LAT (Y171); p-LAT (PhosphoTyr171); Linker for activation of T cell 1; 36 kDa phospho tyrosine adapter protein; LAT 1; LAT1; Linker for activation of T cells; Linker for activation of T cells family member 1; p36 38; pp36; LAT_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:Phospho-LAT (Tyr171)
IR:Immunogen Range:D(p-Y)VN
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:27040
Swiss Prot:O43561
Source:KLH conjugated Synthesised phosphopeptide derived from human LAT isoform b around the phosphorylation site of Tyr171:D(p-Y)VN
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
MCF-7(Human) Cell Lysate at 30 ug
Primary: Anti- Phospho-LAT (Tyr171) (bs-3243R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 29 kD
Observed band size: 34 kD
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