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Anti-CRSP8 antibody (bs-14069R)

Anti-CRSP8 antibody (bs-14069R)

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Anti-CRSP8 antibody

英文名称CRSP8
中文名称转录激活蛋白CRSP8抗体
别    名Cofactor required for Sp1 transcriptional activation subunit 8 (34kD); Cofactor required for Sp1 transcriptional activation subunit 8 34kDa; Cofactor required for Sp1 transcriptional activation subunit 8; CRAP 34; CRAP34; CRSP 34; CRSP 8; CRSP complex subunit 8; CRSP34; MED 27; Med27; MED27_HUMAN; Mediator complex subunit 27; Mediator of RNA polymerase II transcription subunit 27; MGC11274; P37 TRAP/SMCC/PC2 subunit; Transcriptional coactivator CRSP34; TRAP 37; TRAP37.

DATASHEET

Host:Rabbit

Target Protein:CRSP8

IR:Immunogen Range:101-200/311

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:9442

Swiss Prot:Q6P2C8

Source:KLH conjugated synthetic peptide derived from human CRSP8:101-200/311 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Tongue (Mouse) Lysate at 40 ug
Primary: Anti-CRSP8 (bs-14069R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 35 kD
Observed band size: 35 kD

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