Anti-CYP27B1 antibody
| 英文名称 | CYP27B1 |
| 中文名称 | 细胞色素P450 27B1抗体 |
| 别 名 | 1alpha(OH)ase; 25-hydroJNCvitamin D(3) 1-alpha-hydroJNClase; 25-hydroJNCvitamin D-1 alpha hydroJNClase; 25-OHD-1 alpha-hydroJNClase; Calcidiol 1-monooJNCgenase; CP27B_HUMAN; CP2B; CYP1; CYP1ALPHA; CYP27B; Cyp27b1; Cytochrome p450 27B1; Cytochrome p450 27B13; Cytochrome P450 family 27 subfamily B polypeptide 1; Cytochrome P450 subfamily XXVIIB (25-hydroJNCvitamin D-1-alpha-hydroJNClase) polypeptide 1; Cytochrome P450 subfamily XXVIIB polypeptide 1; Cytochrome P450C1 alpha; Cytochrome P450VD1-alpha; mitochondrial; P450C1 alpha; P450c1; P450C1-alpha; P450VD1-alpha; PDDR; VD3 1A hydroJNClase; VDD1; VDDR; VDDR I; VDDRI; VDR. |
DATASHEET
Host:Rabbit
Target Protein:CYP27B1
IR:Immunogen Range:1-100/508
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1594
Swiss Prot:O15528
Source:KLH conjugated synthetic peptide derived from human CYP27B1:1-100/508
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The cytochrome P450 proteins are monooJNCgenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP27B1, a 508-amino acid protein that belongs to the XXVIIB subfamily of the cytochrome P450 family, localizes to the mitochondrion and is expressed in the kidney. The CYP27B1 protein catalyzes the conversion of 25-hydroJNCvitamin D3 (25(OH)D) to 1-alpha,25-dihydroJNCvitamin D3 (1,25(OH)2D) and functions in calcium metabolism, normal bone growth, and tissue differentiation. Mutations in the gene which encodes for CYP27B1 cause vitamin D-dependent rickets type 1 (VDDR-1), also designated pseudovitamin D deficiency rickets (PDDR), an autosomal recessive disease characterized by early onset of rickets with hypocalcemia and muscle weakness.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:Kidney (Mouse) Lysate at 40 ug
Primary: Anti- CYP27B1 (bs-14146R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57kD
Observed band size: 57kD
好评度