Anti-DEXI antibody (bs-14283R)

Anti-DEXI antibody

DATASHEET

Host:Rabbit

Target Protein:DEXI

IR:Immunogen Range:51-95/95

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:28955

Swiss Prot:O95424

Source:KLH conjugated synthetic peptide derived from human DEXI:51-95/95 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:DEXI is a 95 amino acid protein belonging to the DEXI family. Induced by dexamethasone, DEXI is expressed in brain, liver, pancreas, placenta and lung, with highest levels in heart. DEXI is also up-regulated in emphysematous lung compared to normal lung. The gene encoding DEXI maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DEXI) Polyclonal Antibody, Unconjugated (bs-14283R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.