Anti-EXOC3L2 antibody (bs-14660R)

Anti-EXOC3L2 antibody

DATASHEET

Host:Rabbit

Target Protein:EXOC3L2

IR:Immunogen Range:151-250/409

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:90332

Swiss Prot:Q2M3D2

Source:KLH conjugated synthetic peptide derived from human EXOC3L2:151-250/409 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex inhibits tubulin polymerization in vitro, suggesting that the exocyst complex is important for modulating the microtubule dynamics that underlie exocytosis. ExoC3L2 (Exocyst complex component 3-like protein 2), also known as HBV X-transactivated gene 7 protein, is a 409 amino acid protein that is related to the Sec6 component of the exocyst complex.

Size:100ul

Concentration:1mg/ml

Applications:IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Cow
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded (Rat pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (EXOC3L2) Polyclonal Antibody, Unconjugated (bs-14660R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.