Anti-FCN3 antibody
英文名称 | FCN3 |
中文名称 | FCN3蛋白抗体 |
别 名 | Collagen/fibrinogen domain containing lectin 3 p35; Collagen/fibrinogen domain containing protein 3; FCN 3; FCNH; Ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); Ficolin (collagen/fibrinogen domain containing) 3; Ficolin 3; H ficolin; HAKA1; Hakata antigen; MGC22543. |
DATASHEET
Host:Rabbit
Target Protein:FCN3
IR:Immunogen Range:21-120/299
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8547
Swiss Prot:O75636
Source:KLH conjugated synthetic peptide derived from human FCN3:21-120/299
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified. [provided by RefSeq, Jul 2008]
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
A549(Human) Cell Lysate at 30 ug
Primary: Anti-FCN3 (bs-16062R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 30 kD
Observed band size: 30 kD
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