Anti-KIAA1045 antibody (bs-16988R)

Anti-KIAA1045 antibody

DATASHEET

Host:Rabbit

Target Protein:KIAA1045

IR:Immunogen Range:51-150/400

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:23349

Swiss Prot:Q9UPV7

Source:KLH conjugated synthetic peptide derived from human KIAA1045:51-150/400 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:KIAA1045 is a 400 amino acid protein that contains one PHD-type zinc finger. The gene encoding KIAA1045 maps to human chromosome 9p13.3. Chromosome 9 houses over 900 genes and comprises nearly 4% of the human genome. Considered to play a role in gender determination, deletion of the distal portion of chromosome 9p can lead to development of male to female sex reversal, the phenotype of a female with a male JNC genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of a BCR-ABL fusion protein often found in leukemias.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Horse
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:Cerebrum (Mouse)Lysate at 40 ug
Primary: Anti-KIAA1045(bs-16988R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 45kD
Observed band size: 45kD