Anti-KIAA1467 antibody (bs-17008R)

Anti-KIAA1467 antibody

DATASHEET

Host:Rabbit

Target Protein:KIAA1467

IR:Immunogen Range:531-622/622

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:57613

Swiss Prot:A2RU67

Source:KLH conjugated synthetic peptide derived from human KIAA1467:531-622/622 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:KIAA1467 is a 622 amino acid single-pass membrane protein that belongs to the ITFG3 family. KIAA1467 is post-translationally phosphorylated at multiple serine residues and tyrosine 22. The gene encoding KIAA1467 maps to human chromosome 12, which encodes over 1,100 genes and comprises about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism. It is most severe in cases of complete trisomy.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Huvec(Human) Cell Lysate at 30 ug
Panc-1 Cell Lysate at 30 ug
Primary: Anti-KIAA1467 (bs-17008R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 67 kD
Observed band size: 67kD