Anti-hnRNP M3-M4 antibody (bs-17336R)

Anti-hnRNP M3-M4 antibody

DATASHEET

Host:Rabbit

Target Protein:hnRNP M3-M4

IR:Immunogen Range:2-100/730

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:4670

Swiss Prot:P52272

Source:KLH conjugated synthetic peptide derived from human hnRNP M3-M4:2-100/730 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Rabbit
Sheep
Rhesus monkey, Gorilla, Chinese Hamster, Orangutan, Elephant.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
BRL-3A(Rat) Cell Lysate at 30 ug
Primary: Anti-hnRNP M3-M4 (bs-17336R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 77 kD
Observed band size: 73 kD