Anti-HLADQA1 + HLADQA2 antibody
| 英文名称 | HLADQA1 + HLADQA2 |
| 中文名称 | 组织相容性抗原DQA1/DQA2抗体 |
| 别 名 | CD; CELIAC1; DC-1 alpha; DC-1 alpha chain; DQ-A1; DX alpha chain; DX-ALPHA; FLJ27088; FLJ27328; GSE; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA class II histocompatibility antigen, DQ alpha 2 chain; HLA class II histocompatibility antigen, DQ(6) alpha chain; HLA class II histocompatibility antigen, DQ(W3) alpha chain; HLA-DCA; HLA-DQA; HLA-DQA2; HLA-DXA; leucocyte antigen DQA1; leukocyte antigen alpha chain; major histocompatibility complex, class II, DQ alpha 1; major histocompatibility complex, class II, DQ alpha 2; MGC149527; MHC class II antigen; MHC class II DQA1; MHC class II DQA2; MHC class II HLA-D alpha glycoprotein; MHC class II HLA-DQ-alpha-1; MHC class II surface glycoprotein; MHC HLA-DQ alpha. |
DATASHEET
Host:Rabbit
Target Protein:HLADQA1 + HLADQA2
IR:Immunogen Range:51-150/254
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3117
3118
Swiss Prot:P01906
Source:KLH conjugated synthetic peptide derived from human HLADQA1 + HLADQA2:51-150/254
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008]
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Cross Reactive Species:Human
Chimpanzee, Cynomolgus Monkey.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
A431(Human) Cell Lysate at 30 ug
Primary: Anti-HLADQA1 + HLADQA2 (bs-18043R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 26 kD
Observed band size: 36 kD
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