Anti-C12orf72 antibody (bs-18117R)

Anti-C12orf72 antibody

DATASHEET

Host:Rabbit

Target Protein:C12orf72

IR:Immunogen Range:61-160/262

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:254013

Swiss Prot:Q8IXQ9

Source:KLH conjugated synthetic peptide derived from human C12orf72:61-160/262 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. ARHGAP36 (Rho GTPase activating protein 36) is a 547 amino acid protein that contains one Rho-GAP domain. Conserved in chimpanzee, dog, cow, mouse and rat, ARHGAP36 exists as five alternatively spliced isoforms and is encoded by a gene that maps to human chromosome Xq26.1. Chromosome X consists of nearly 153 million base pairs encoding approximately 1,000 genes. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are X chromosome-linked conditions that affect males more frequently because males carry a single X chromosome.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded (Rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (C12orf72) Polyclonal Antibody, Unconjugated (bs-18117R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.