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Anti-LXR beta antibody (bs-18450R)

Anti-LXR beta antibody (bs-18450R)

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Anti-LXR beta antibody

英文名称LXR beta
中文名称肝脏X受体β抗体
别    名Liver X nuclear receptor beta; Liver X receptor beta; Liver X receptor beta; LX receptor beta; LXR b; LXR beta; LXRB; NER 1; NER; NER I; NER1; NERI; NR1H 2; NR1H; NR1H2; NR1H2 protein; NR1H2_HUMAN; Nuclear orphan receptor LXR beta; Nuclear orphan receptor LXR beta; Nuclear receptor NER; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; OR-1; OJNCsterols receptor LXR beta; OJNCsterols receptor LXR-beta; RIP 15; RIP15; steroid hormone nuclear receptor NER; Ubiquitously expressed nuclear receptor; Ubiquitously-expressed nuclear receptor; UENR; UNR.  

DATASHEET

Host:Rabbit

Target Protein:LXR beta

IR:Immunogen Range:361-460/460

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:7376

Swiss Prot:P55055

Source:KLH conjugated synthetic peptide derived from human LXR beta:361-460/460 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample: small intestine (Mouse) Lysate at 40 ug
Primary: Anti-LXR beta(bs-18450R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD

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