Anti-LXR alpha + LXR beta antibody
| 英文名称 | LXR alpha + LXR beta |
| 中文名称 | 肝脏X受体α+肝脏X受体β抗体 |
| 别 名 | Liver X receptor alpha; Liver X receptor alpha; Liver X receptor beta; LXR a; LXR; LXR b; LXRa; LXRalpha; LXRb; LXRbeta; NER; NERI; NR1H2; NR1H3; Nuclear orphan receptor LXR alpha; Nuclear orphan receptor LXR beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Nuclear receptor subfamily 1 group H member 3; OJNCsterols receptor LXR alpha; OJNCsterols receptor LXR beta; RIP15; RLD1; Ubiquitously expressed nuclear receptor; UNR. |
DATASHEET
Host:Rabbit
Target Protein:LXR alpha + LXR beta
IR:Immunogen Range:51-150/447
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10062
Swiss Prot:Q13133
Source:KLH conjugated synthetic peptide derived from human LXR alpha:51-150/447
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:LXR alpha and LXR beta are orphan receptors. Interaction with RXR shifts RXR from its role as a silent DNA binding partner to an active ligand binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4 type response elements characterized by direct repeats of two similar hexanuclotide half sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis. LXR alpha: Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals. LXR beta: Ubiquitously expressed.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Xenopus laevis.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Heart (Mouse) Lysate at 40 ug
Primary: Anti-LXR alpha + LXR beta (bs-18451R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD
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