Anti-phospho-MDC1 (Thr4) antibody
| 英文名称 | phospho-MDC1 (Thr4) |
| 中文名称 | 磷酸化DNA损伤关卡蛋白1抗体 |
| 别 名 | MDC1 (phospho T4); p-MDC1 (phospho T4); DKFZp781A0122; Homologue to Drosophila photoreceptor protein calphotin; KIAA0170; KIAA0170; MDC 1; Mdc1; MDC1_HUMAN; Mediation of DNA damage checkpoint 1; Mediator of DNA damage checkpoint 1; Mediator of DNA Damage Checkpoint Protein 1; Mediator of DNA Damage Checkpoint Protein 1; NFBD 1; NFBD1; NFBD1; Nuclear factor with BRCT domains 1; Nuclear Factor with BRCT Domains Protein 1; Nuclear Factor with BRCT Domains Protein 1. |
DATASHEET
Host:Rabbit
Target Protein:phospho-MDC1 (Thr4)
IR:Immunogen Range:ED(p-T)QA
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9656
Swiss Prot:Q14676
Source:KLH conjugated synthesised phosphopeptide derived from human MCSF Receptor around the phosphorylation site of Thr4:ED(p-T)QA
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008]
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:A431(Human)Cell Lysate at 40 ug
Primary: Anti-p-MDC1(Thr4)(bs-18742R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 227kD
Observed band size: 227kD
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