Anti-S1P/Subtilisin isozyme 1 antibody (bs-19355R)

Anti-S1P/Subtilisin isozyme 1 antibody

DATASHEET

Host:Rabbit

Target Protein:S1P/Subtilisin isozyme 1

IR:Immunogen Range:861-960/1052

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:8720

Swiss Prot:Q14703

Source:KLH conjugated synthetic peptide derived from human S1P/Subtilisin isozyme 1:861-960/1052 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Adrenal gland (Mouse) Lysate at 40 ug
Primary: Anti-S1P/Subtilisin isozyme 1  (bs-19355R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 96 kD
Observed band size: 126 kD