Anti-UMPS antibody (bs-8110R)

Anti-UMPS antibody 

DATASHEET

Host:Rabbit

Target Protein:UMPS

IR:Immunogen Range:351-450/480

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:7372

Swiss Prot:P11172

Source:KLH conjugated synthetic peptide derived from human UMPS:351-450/480 

Purification:affinity purified by Protein A

Storage:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboJNClase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Rabbit
Sheep
Cynomolgus Monkey, Rhesus monkey.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Hela(Human)Cell Lysate at 40 ug
293T (Human) Cell Lysate at 40 ug
Primary: Anti-UMPS(bs-8110R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 52kD
Observed band size: 52kD

Sample:
Hela(Human)Cell Lysate at 40 ug
293T (Human) Cell Lysate at 40 ug
Primary: Anti-UMPS(bs-8110R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 52kD
Observed band size: 52kD