Anti-CYP3A1 antibody
| 英文名称 | CYP3A1 |
| 中文名称 | 细胞色素CYP3A1抗体 |
| 别 名 | Cytochrome P450 3A1; CYP3A; CYP3A1; cytochrome P450, family 3, subfamily a, polypeptide 1; glucocorticoid inducible P450; HLP; MGC126680; NF 25; NF25; Nifedipine oxidase; Niphedipine oxidase; P450 III steroid inducible; P450 PCN(PCNC inducible); P450 PCN1; P450C3; P450PCN1; Quinine 3 monooJNCgenase; TaurochenodeoJNCcholate 6 alpha hydroJNClase; CP3A1_RAT. |
DATASHEET
Host:Rabbit
Target Protein:CYP3A1
IR:Immunogen Range:231-330/504
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:25642
Swiss Prot:P04800
Source:KLH conjugated synthetic peptide derived from rat CYP3A1:231-330/504
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CYP3A proteins are P450 monooJNCgenases and in animals, P450 enzymes serve two major functions: biosynthesis of steroids, fatty acids and bile acids, and the metabolism of endogenous and exogenous substrates. A wide variety of exogenous substrates are metabolized by P450 enzymes, including toxins and drugs. The four major families involved in drug metabolism are CYP1, 2, 3 and 4. The hepatic CYP3A1 protein is detected throughout ciliated and nonciliated cells in seven-day-old rats, and is only detected in the apex of these cells in adult rats. Rat CYP3A1 and CYP3A2 share 89% homolgy, but differ by three out of five of their C-terminal residues.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Rat
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For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Liver (Rat)Lysate at 40 ug
Cerebrum (Rat)Lysate at 40 ug
Primary: Anti-CYP3A1(bs-20586R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 57kD
Observed band size: 57kD
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