Anti-Phospho-Beta-Catenin (Ser552) antibody
| 英文名称 | Phospho-Beta-Catenin (Ser552) |
| 中文名称 | 磷酸化β连环素蛋白抗体 |
| 别 名 | beta Catenin (phospho S552); beta Catenin (phospho Ser552); p-beta Catenin (S552); p-beta Catenin (Ser552); p-beta Catenin (phospho S552); beta-catenin; CHBCAT; CTNNB1; CTNNB; PRO2286; Cadherin associated protein; Catenin (cadherin associated protein), beta 1, 88kDa; Catenin beta 1; Catenin beta-1; CATNB; CTNB1_HUMAN; DKFZp686D02253; FLJ25606; FLJ37923; b-catenin; Catenin-β; Catenin β. |
DATASHEET
Host:Rabbit
Target Protein:Phospho-Beta-Catenin (Ser552)
IR:Immunogen Range:RT(p-S)MG
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1499
Swiss Prot:P35222
Source:KLH conjugated synthesised phosphopeptide derived from human beta Catenin around the phosphorylation site of Ser552:RT(p-S)MG
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009].
Size:100ul
Concentration:1mg/ml
Applications:IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Pig
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Blank control:Hela (fixed with 2% paraformaldehyde (10 min) , then permeabilized with 0.3%tritionx-100 for 5 min at room temperature).
Primary Antibody:Rabbit Anti-Phospho-Beta-Catenin (Ser552) antibody (bs-20604R,Green); Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions );
Secondary Antibody: Goat anti-rabbit IgG-FITC), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.
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