Anti-Macrophage mannose receptor 1 antibody (bs-23178R)

Anti-Macrophage mannose receptor 1 antibody

DATASHEET

Host:Rabbit

Target Protein:Macrophage mannose receptor 1

IR:Immunogen Range:1231-1292/1292

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:4360

Swiss Prot:P22897

Source:KLH conjugated synthetic peptide derived from human Macrophage mannose receptor 1:1231-1292/1292 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq].

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Liver (Rat) Lysate at 40 ug
Primary: Anti-Macrophage mannose receptor 1 (bs-23178R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 160 kD
Observed band size: 160 kD