Anti-Caveolin-1 antibody (bs-23173R)

Anti-Caveolin-1 antibody

DATASHEET

Host:Rabbit

Target Protein:Caveolin-1

IR:Immunogen Range:2-80/178

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:857

Swiss Prot:Q03135

Source:KLH conjugated synthetic peptide derived from human Caveolin-1:2-80/178 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq].

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Lane 1: Lung (Rat) Lysate at 40 ug
Lane 2: Kidney (Rat) Lysate at 40 ug
Lane 3: Spleen (Rat) Lysate at 40 ug
Primary: Anti-Caveolin-1 (bs-23173R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 22 kD
Observed band size: 22 kD