Anti-ZNT8 antibody
英文名称 | ZNT8 |
中文名称 | 锌转运体8蛋白抗体 |
别 名 | SLC30A8; solute carrier family 30 (zinc transporter), member 8; Solute carrier family 30 member 8; Zinc transporter 8; zinc transporter ZnT-8; ZnT-8; ZNT8; ZNT8_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:ZNT8
IR:Immunogen Range:221-320/369
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:169026
Swiss Prot:Q8IWU4
Source:KLH conjugated synthetic peptide derived from human ZNT8 :221-320/369
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:ZNT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
K562(Human) Cell Lysate at 30 ug
Primary: Anti-ZNT8 (bs-23854R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kD
Observed band size: 43 kD
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