Anti-SCXA antibody (bs-23616R)

Anti-SCXA antibody

DATASHEET

Host:Rabbit

Target Protein:SCXA

IR:Immunogen Range:21-120/201

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:642658

Swiss Prot:Q7RTU7

Source:KLH conjugated synthetic peptide derived from human SMCR7L:21-120/201 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Transcription factors are proteins that bind DNA adjacent to genes and control the production of mRNA transcripts. Scleraxis (basic helix-loop-helix transcription factor scleraxis) is a 201 amino acid protein that dimerizes with another bHLH protein to initiate transcription. Scleraxis is known to play a role in formation of mesoderm and somite-derived chondrogenic lineages. Scleraxis localizes to the nucleus and contains 1 bHLH domain. bHLH transcription factors, in general, function in cellular differentiation, proliferation, and oncogene regulation. The gene encoding Scleraxis maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Horse
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Hela(Human) Cell Lysate at 30 ug
Primary: Anti- SCXA (bs-23616R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 22 kD
Observed band size: 22 kD