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Anti-GLK antibody (bs-23984R)

Anti-GLK antibody (bs-23984R)

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Anti-GLK antibody 

英文名称GLK
中文名称葡萄糖激酶抗体
别    名Glucokinase; ATP D hexose 6 phosphotransferase; GCK; GK; GLK; Glucokinase isoform 1; Hexokinase 4; Hexokinase D; Hexokinase D pancreatic isozyme; Hexokinase type IV; Hexokinase4; HexokinaseD; HHF 3; HHF3; HK 4; HK IV; HK4; HXKP; Maturity onset diabetes of the young 2; MODY 2; MODY2; GLUKA; RNGK2; HXK4_HUMAN.  

DATASHEET

Host:Rabbit

Target Protein:GLK

IR:Immunogen Range:231-330/465

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2645

Swiss Prot:P35557

Source:KLH conjugated synthetic peptide derived from human GLK:231-330/465 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of this gene results in three tissue specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose 6 phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non insulin dependent diabetes mellitus, also called maturity onset diabetes of the young, type 2; mutations have also been associated with persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)

Cross Reactive Species:Human
Mouse
Rat
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti- GLK (bs-23984R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD

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Anti-GLK antibody (bs-23984R)

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