Anti-Cytochrome P450 2D1 antibody (bs-23771R)

Anti-Cytochrome P450 2D1 antibody

DATASHEET

Host:Rabbit

Target Protein:Cytochrome P450 2D1

IR:Immunogen Range:101-200/504

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:266684

Swiss Prot:P10633

Source:KLH conjugated synthetic peptide derived from rat Cytochrome P450 2D1:101-200/504 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The cytochrome P450 superfamily of heme thiolate mono oJNCgenases play a key role in the oxidative metabolism of many endogenous and exogenous molecules, and are classified by their primary structure into four main groups. It is an ancient superfamily, which has been identified in prokaryotes and in many types of eukaryotic cells.
The CYP2A sub family is found in the liver, and recently in the nasal mucosa where they are involved in the metabolism of inhaled xenobiotics and nicotine. CYP2B proteins are found in the liver, where they are involved in the metabolism of hepatic drugs, and in the lung and brain, whereas the CYP2C proteins are involved in the metabolism of anti depressants. CYP2E1 is alcohol inducible, and found principally in the liver.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Rat
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
BRL-3A(Rat) Cell Lysate at 30 ug
Primary: Anti-Cytochrome P450 2D1 (bs-23771R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 58 kD