Anti-Notch 2 antibody
| 英文名称 | Notch 2 |
| 中文名称 | 跨膜受体蛋白Notch-2抗体 |
| 别 名 | Neurogenic locus notch homolog protein 2; activated Notch 2; Notch2; hN2; Notch 2 extracellular truncation; Notch 2 intracellular domain; AGS2; hN2; Motch B; N2 antibody neurogenic locus notch homolog protein 2; NOTC2_HUMAN; Notch 2; Notch Drosophila homolog 2; Notch homolog 2; Notch homolog 2 Drosophila. |
DATASHEET
Host:Rabbit
Target Protein:Notch 2
IR:Immunogen Range:2070-2170/2471
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4853
Swiss Prot:Q04721
Source:KLH conjugated synthetic peptide derived from human Notch 2:2070-2170/2471
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Lung (Mouse) Lysate at 40 ug
Primary: Anti- Notch 2 (bs-21664R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 262 kD
Observed band size: 262 kD
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