Anti-phospho-heterochromatin protein 1 (pTyr41) antibody
| 英文名称 | phospho-heterochromatin protein 1 (pTyr41) |
| 中文名称 | 异染色质蛋白1磷酸化抗体（果蝇） |
| 别 名 | Antigen p25; Cbx 5; Cbx5 antibody Chromobox homolog 5 (Drosophila HP1 alpha); Chromobox homolog 5 (HP1 alpha homolog Drosophila); Chromobox homolog 5; Chromobox protein homolog 5; Chromobox protein homologue 5 ; Heterochromatin protein 1 alpha; Heterochromatin protein 1; Heterochromatin protein 1 homolog alpha; HP 1; HP 1A; HP1 alpha homolog ; HP1A ; HP1Hs alpha; HP1Hs-alpha. |
DATASHEET
Host:Rabbit
Target Protein:phospho-heterochromatin protein 1 (pTyr41)
IR:Immunogen Range:VE(p-Y)YL
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:N/A
Swiss Prot:P05205
Source:KLH conjugated Synthesised phosphopeptide derived from Fruit Fly HP1 around the phosphorylation site of Tyr41:VE(p-Y)YL
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboJNC-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Fruit Fly
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For research use only. Not intended for diagnostic or therapeutic use.
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