Anti-MAD1 antibody
| 英文名称 | MAD1 |
| 中文名称 | 有丝分裂抑制缺陷蛋白1抗体 |
| 别 名 | mitosis arrest deficiency 1; hMAD1; HsMAD1; MAD1L1; Mitotic arrest deficient 1; Mitotic checkpoint MAD1 protein homolog; Mitotic spindle assembly checkpoint protein MAD1; PIG9; Tax binding protein 181; TP53I9 ; Tumor protein p53 inducible protein 9; TXBP181; MD1L1_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:MAD1
IR:Immunogen Range:101-200/718
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8379
Swiss Prot:Q9Y6D9
Source:KLH conjugated synthetic peptide derived from human MAD1:101-200/718
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators. Like other spindle checkpoint mutants, MAD1 loss-of-function mutants are sensitive to benomyl and cannot delay cell division in response to spindle depolymerization. Mad1p becomes hyperphosphorylated upon spindle depolymerization.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
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