Anti-phospho C-Myc (Thr58 / Ser62) antibody
| 英文名称 | phospho C-Myc (Thr58 / Ser62) |
| 中文名称 | 磷酸化致癌基因C-Myc抗体 |
| 别 名 | c-Myc (phospho T58 + S62); Myc(Phospho-Thr58/pSer62); Myc(Phospho-T58/S62); p-Myc(Thr58/pSer62); p-Myc(T58/S62); AU016757; Avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; Cellular myelocytomatosis oncogene; MGC105490; MRTL; Myc protein; Myc proto oncogene protein; Myc-related translation/localization regulatory factor; Myc2; myca; Myelocytomatosis oncogene a; Myelocytomatosis oncogene; Niard; Nird; Oncogene Myc; Protooncogene homologous to myelocytomatosis virus; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; v myc avian myelocytomatosis viral oncogene homolog; v myc myelocytomatosis viral oncogene homolog (avian); V-Myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian); zc-myc; MYC_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:phospho C-Myc (Thr58 / Ser62)
IR:Immunogen Range:LP(p-T)PPL(p-S)PS
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4609
Swiss Prot:P01106
Source:KLH conjugated Synthesised phosphopeptide derived from human c-Myc around the phosphorylation site of Thr58 and Ser62:LP(p-T)PPL(p-S)PS
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.
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