Anti-Phospho-Acetyl Coenzyme A carboJNClase alpha (Ser78) antibody (bs-3036R)

Anti-Phospho-Acetyl Coenzyme A carboJNClase alpha (Ser78) antibody 

DATASHEET

Host:Rabbit

Target Protein:Phospho-Acetyl Coenzyme A carboJNClase alpha (Ser78)

IR:Immunogen Range:PA(p-S)HK

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:31

Swiss Prot:Q13085

Source:KLH conjugated Synthesised phosphopeptide derived from human Acetyl Coenzyme A carboJNClase alpha around the phosphorylation site of Ser78:PA(p-S)HK 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Acetyl-CoA carboJNClase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboJNClation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Pig
Horse
.

For research use only. Not intended for diagnostic or therapeutic use.