Anti-ARHI antibody
英文名称 | ARHI |
中文名称 | 抑癌基因ras同源家族1抗体 |
别 名 | DIRA3; DIRAS family GTP binding RAS like 3; Distinct subgroup of the Ras family member 3; GTP binding protein Di Ras3; NOEY2; Rho related GTP binding protein RhoI; RHOI; DIRA3_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:ARHI
IR:Immunogen Range:131-229/229
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9077
Swiss Prot:O95661
Source:KLH conjugated synthetic peptide derived from human ARHI:131-229/229
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:ARHI contains a highly conserved GTP-binding domain, a putative effector domain distinct from that of RAS and RAP proteins, and a C-terminal membrane localization motif. ARHI mRNA is detected in all normal breast and ovarian epithelial cell cultures tested, as well as in normal ovary, heart, liver, pancreas and brain however ARHI expression is down-regulated in breast and ovarian tumors. Reactivation of ARHI expression in breast cancer cells is associated with increased histone H3 acetylation and decreased lysine 9 methylation of histone H3.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
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