Anti-Phospho-Lck (Tyr505) antibody
| 英文名称 | Phospho-Lck (Tyr505) |
| 中文名称 | 磷酸化淋巴细胞特异性蛋白酪氨酸激酶抗体 |
| 别 名 | LCK (phospho Y505); LCK (phospho Tyr505); p-LCK (Tyr505); p56-LCK; Lymphocyte cell-specific protein-tyrosine kinase; T cell-specific protein-tyrosine kinase; Lck p56; LSK; Lymphocyte Specific Protein Tyrosine Kinase; Membrane associated protein tyrosine kinase; Oncogene lck; P56 LCK; p56(LSTRA) protein tyrosine kinase; p56lck; pp58 lck; pp58lck; Proto oncogene tyrosine protein kinase LCK; Protooncogene tyrosine protein kinase LCK; T cell specific protein tyrosine kinase; T lymphocyte specific protein tyrosine kinase p56lck; YT 16; YT16; LCK_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:Phospho-Lck (Tyr505)
IR:Immunogen Range:GQ(P-Y)QP
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3932
Swiss Prot:P06239
Source:KLH conjugated synthesised phosphopeptide derived from human Lck around the phosphorylation site of Tyr505:GQ(P-Y)QP
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.
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