Anti-Phospho-AKT1S1 (Thr246) antibody
| 英文名称 | Phospho-AKT1S1 (Thr246) |
| 中文名称 | 磷酸化蛋白激酶AKT底物1抗体 |
| 别 名 | PRAS40 (Phospho Thr246); PRAS40 (Phospho T246); AKT1 substrate 1 (proline rich); PRAS40; AKT1 substrate 1; AKT1-S1; AKT1S-1; AKT1S 1; AKT1 S1; Lobe; PRAS 40; PRAS-40; Proline rich akt substrate; 40 kDa proline rich AKT substrate; 40 kDa proline-rich AKT substrate; AKT1 substrate 1; AKTS1_HUMAN; MGC2865; Proline rich Akt substrate 40 kDa; Proline-rich AKT1 substrate 1. |
DATASHEET
Host:Rabbit
Target Protein:Phospho-AKT1S1 (Thr246)
IR:Immunogen Range:LN(p-T)SD
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:84335
Swiss Prot:Q96B36
Source:KLH conjugated Synthesised phosphopeptide derived from human PRAS40 around the phosphorylation site of Thr246:LN(p-T)SD
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Proline Rich Akt Substrate (PRAS40) is a 40 kDa substrate of Akt. Akt and PRAS40 can be found in the phosphoinositide 3 kinase (PI3K) pathway, which plays a role in glucose uptake, cell growth, and apoptosis inhibition. PRAS40 is a 14-3-3 binding protein that reacts with insulin, but whose precise function is not yet known. It may bind SH3 and WW domain containing proteins resulting in a change of function. Activated Akt phosphorylates PRAS40 on threonine 246. Mutation of PRAS40 threonine 246 has been shown to be apoptotic.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
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