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Anti-Phospho-RSK3 (Thr353 + Thr356) antibody (bs-3365R)

Anti-Phospho-RSK3 (Thr353 + Thr356) antibody (bs-3365R)

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Anti-Phospho-RSK3 (Thr353 + Thr356) antibody

英文名称Phospho-RSK3 (Thr353 + Thr356)
中文名称磷酸化核糖体蛋白S6激酶家族RSK3抗体
别    名RSK3 (Phospho T353 + T356); Phospho-RSK3 (Thr353 + Thr356); 90 kDa ribosomal protein S6 kinase 2; HU 2; KS6A2_HUMAN; MAP kinase activated protein kinase 1c; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; MAPKAPK1C; p90-RSK 2; p90RSK 2; p90RSK2; pp90RSK 3; pp90RSK3; Ribosomal protein S6 kinase alpha-2; Ribosomal S6 kinase 3; RPS6KA2; RSK 3; RSK-3; S6K alpha 2; S6K alpha; S6K-alpha-2.  

DATASHEET

Host:Rabbit

Target Protein:Phospho-RSK3 (Thr353 + Thr356)

IR:Immunogen Range:EF(p-T)AR(p-T)PT

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:6196

Swiss Prot:Q15349

Source:KLH conjugated Synthesised phosphopeptide derived from human RSK3 around the phosphorylation site of Thr353/356:EF(p-T)AR(p-T)PT 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:RSK3(Ribosomal S6 kinase 3)is a member of a family of 90-kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases that are activated in response to mitogenic stimuli, including extracellular signal-regulated protein kinases Erk1 and Erk2. Rsk3 is a distinct isoform of p90Rsk that translocates to the cell nucleus, phosphorylates potential nuclear targets and may have a unique upstream activator. Several sites, such as Ser380, Thr359, Ser363 and Thr573, are important for its activation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Sheep
Guinea Pig
.

For research use only. Not intended for diagnostic or therapeutic use.

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