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Anti-phospho-eIF4EBP1 (Ser65 + Thr70) antibody (bs-3720R)

Anti-phospho-eIF4EBP1 (Ser65 + Thr70) antibody (bs-3720R)

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Anti-phospho-eIF4EBP1 (Ser65 + Thr70) antibody

英文名称phospho-eIF4EBP1 (Ser65 + Thr70)
中文名称磷酸化eIF4E结合蛋白抗体
别    名eIF4EBP1 (phospho S65/Th70); eIF4EBP1 (phospho Ser65/Thr70); p-eIF4EBP1 (Ser65/Thr70); eIF4EBP1; Eukaryotic translation initiation factor 4E binding protein 1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E BP1; 4EBP1; BP 1; BP1; eIF4E binding protein 1; eIF4E-binding protein 1; Eukaryotic translation initiation factor 4E binding protein 1; MGC4316; PHAS I; PHASI; PHAS-I; PHAS; 4E-BP1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; Phosphorylated heat and acid stable protein regulated by insulin 1; 4EBP1_HUMAN. 

DATASHEET

Host:Rabbit

Target Protein:phospho-eIF4EBP1 (Ser65 + Thr70)

IR:Immunogen Range:RN(p-S)PVTK(p-T)PP

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:13685

Swiss Prot:Q60876

Source:KLH conjugated Synthesised phosphopeptide derived from mouse 4EBP1 around the phosphorylation site of Ser65/Thr70:RN(p-S)PVTK(p-T)PP 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.

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