Anti-eI4EBP2 antibody
英文名称 | eI4EBP2 |
中文名称 | eIF4E结合蛋白2抗体 |
别 名 | Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway.Full=Eukaryotic translation initiation factor 4E-binding protein 2; 4E-BP2; eIF4E-binding protein 2; 4EBP2_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:eI4EBP2
IR:Immunogen Range:21-120/120
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1979
Swiss Prot:Q13542
Source:KLH conjugated synthetic peptide derived from human 4E-BP2:21-120/120
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Cow
.
For research use only. Not intended for diagnostic or therapeutic use.
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