Anti-phospho-CARM1 (Ser228) antibody
| 英文名称 | phospho-CARM1 (Ser228) |
| 中文名称 | 磷酸化蛋白精氨酸N甲基4抗体 |
| 别 名 | CARM1 (phospho Ser228); CARM1 (phospho S228); CARM1_HUMAN; Coactivator associated arginine methyltransferase 1; Coactivator-associated arginine methyltransferase 1; Histone arginine methyltransferase CARM 1; Histone arginine methyltransferase CARM1; Histone-arginine methyltransferase CARM1; PRMT 4; Protein arginine methyltransferase; Protein arginine N methyltransferase 4; Protein arginine N-methyltransferase 4. |
DATASHEET
Host:Rabbit
Target Protein:phospho-CARM1 (Ser228)
IR:Immunogen Range:VK(p-S)NN
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10498
Swiss Prot:Q86X55
Source:KLH conjugated Synthesised phosphopeptide derived from human CARM1 around the phosphorylation site of Ser228:VK(p-S)NN
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' and activates transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
好评度