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Anti-phospho-MAP4K4 (Ser631) antibody (bs-5492R)

Anti-phospho-MAP4K4 (Ser631) antibody (bs-5492R)

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Anti-phospho-MAP4K4 (Ser631) antibody 

英文名称phospho-MAP4K4 (Ser631)
中文名称磷酸化丝裂原活化蛋白激酶MAP4K4抗体
别    名MAP4K4(phospho S631); p-MAP4K4(phospho S631); Hepatocyte progenitor kinase like/germinal center kinase like kinase; HGK; HPK/GCK like kinase; HPK/GCK like kinase HGK; KIAA0687; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; Mitogen activated protein kinase kinase kinase kinase 4; Nck interacting kinase; NIK.  

DATASHEET

Host:Rabbit

Target Protein:phospho-MAP4K4 (Ser631)

IR:Immunogen Range:SR(p-S)PV

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:9448

Swiss Prot:O95819

Source:KLH conjugated Synthesised phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser631:SR(p-S)PV 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Horse
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.

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