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Anti-phospho-MAX protein (Tyr123) antibody (bs-5425R)

Anti-phospho-MAX protein (Tyr123) antibody (bs-5425R)

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Anti-phospho-MAX protein (Tyr123) antibody

英文名称phospho-MAX protein (Tyr123)
中文名称磷酸化Myc基因相关X因子抗体
别    名bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; Class D basic helix-loop-helix protein 4; Helix loop helix zipper protein; MAX protein; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; Myc associated factor X; Myc-associated factor X; MAX_HUMAN; Myc binding novel HLH/LZ protein; Orf 1; Orf1; Protein max.  

DATASHEET

Host:Rabbit

Target Protein:phospho-MAX protein (Tyr123)

IR:Immunogen Range:SL(p-Y)TN

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:4149

Swiss Prot:P61244

Source:KLH conjugated Synthesised phosphopeptide derived from human MAX protein around the phosphorylation site of Tyr123:SL(p-Y)TN 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:MAX protein is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Horse
.

For research use only. Not intended for diagnostic or therapeutic use.

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