Anti-ASBT antibody
| 英文名称 | ASBT |
| 中文名称 | 顶膜钠依赖性胆盐转运体蛋白抗体 |
| 别 名 | SLC10A2; Apical sodium dependent bile acid transporter; Apical sodium- dependent bile acid transporter; IBAT; ileal apical sodium-dependent bile acid transporter; Ileal sodium dependent bile acid transporter; Ileal sodium-dependent bile acid transporter; Ileal sodium/bile acid cotransporter; ISBT; Na+ bile acid cotransporter; Na+ dependent ileal bile acid transporter; NTCP2; Sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family); Solute carrier family 10 member 2. |
DATASHEET
Host:Rabbit
Target Protein:ASBT
IR:Immunogen Range:131-230/348
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6555
Swiss Prot:Q12908
Source:KLH conjugated synthetic peptide derived from human ASBT:131-230/348
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:SLC10A2 plays a critical role in reabsorption of bile acids from the the small intestine lumen. Passive flow of sodium ions down their concentration gradient is coupled to bile acid movement, resulting in an increase in the concentration of bile acids in the interior of the cell. This action conserves the body's pool of re-circulating bile acid. SLC10A2 also plays a key role in cholesterol metabolism as cholesterol is the precursor molecule in bile acid synthesis mediated by CYP7A and FXR.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
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